What are some important considerations in the production of bulk enzymes for industrial food applications?

What are some important considerations in the production of bulk enzymes for industrial food applications? With some specific examples, compare and contrast production of these enzymes with the production of therapeutic enzymes. What are the best sources for these enzymes? How does a company balance safety/purity and production cost? How can large-scale production be optimized and production of the enzymes maximized?

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