Part II Questions (11pts):
Based on your in-class knowledge, the content of the articles, and any other sources that you can
utilize, answer the following questions:
1. What does seropositive mean and how is a person tested for HIV? (2pts)
2. Often, people must wait at least six weeks after suspected exposure before getting an HIV
test. Why is this waiting period necessary? (1pt)
3. How is HIV able to circumvent the host immune response? (give at least 2 examples and
explain them) (4pts)
4. How does SIV differ from HIV? (2pts)
5. The Dr. Hahn’s team of researchers found the different prevalence of SIV in the different
chimpanzee communities, 35% in three chimpanzee communities, 4-5% in two
chimpanzee communities, and none in the remaining five chimpanzee communities.
What is the significance of this finding? (2pts)
Part II: Scientific papers related to this case study, makes for good reading:
1. Hahn, B., Shaw, G.M., De Cock, K.M., Sharp, P.M. 2000 AIDS as a Zoonosis: scientific
and public health implications. Science (Compass Reviews) 287, 607-614.
2. Gao, F. et al. 1999. Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes.
Nature 397 (436-441).
3. Wolfe, N. et al. 2004 Naturally acquired simian retrovirus infections in central African
hunters. The Lancet 363 (932-936
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