cancer clinlic trails

For this assignment, you will be learning a bit more about a specific type of cancer, as well as how new treatments for cancer are developed. Before beginning, watch this short video about clinical trials:

Post Requirements:

This assignment requires two posts, each completed individually.

First Post – Due Thursday

For this post, you will be focusing on one of the following types of cancer. Note that no credit will be given for duplicate posts about the same type of cancer, so check to see what your groupmates have posted before selecting a type of cancer. You may wish to submit a placeholder post while you work on the rest of your response.

Colorectal cancer
Myeloma
Pancreatic cancer
Lung cancer
Breast cancer
Be sure to cite your sources fully, including in-text citations and a full reference list at the end for full credit.

Write a 3-4 sentence summary describing this type of cancer.
List the risk factors for this type of cancer.
What are two ways that this type of cancer can be prevented?
Use MedGen to search for this type of cancer. Click on the first search result. Click on one of the genes that is associated with this type of cancer.
What is the official full name of this gene?
Read through the summary. What cellular processes and/or functions is this gene involved in? For example, it is important for cell survival? Apoptosis? Microtubule formation?
Use ClinicalTrials.gov to find a clinical trial that is available for this type of cancer. Choose a trial that is currently looking for participants.
Include the title and a link to the clinical trial in your post.
Where is this study being conducted?
What is the study type? Is it interventional, observational, or expanded access? What does this mean?
What is the intervention or treatment being studied?
What phase is the study in? What is the purpose of this phase?
What are the eligibility criteria?
What is the expected enrollment?
Second Post – Due Sunday

Choose one classmate’s post to which to respond. Try to respond to someone that hasn’t yet received a response. You will be doing a bit of additional research about the type of cancer your classmate posted about as well as the clinical trial that they shared.

To account for the diverse lived experiences and exposures of various populations, clinical trials must be appropriately inclusive of racial and ethnic minority groups, as well as other populations experiencing health disparities, including sexual and gender minority or socioeconomically disadvantaged populations. One way that researchers can work to create representative patient data is to know what “representative” means for the health condition of interest and to set intentional recruitment goals for clinical trials.
Use United States Cancer Statistics to look up the incidence rates for this type of cancer in your state of residence. If you reside outside of the United States, you can use California. Refer to the chart showing ‘Rate of New Cancers By Sex and Race and Ethnicity.’ For which two groups are there the highest incidence rates? For which two groups are there the lowest incidence rates? Include a screenshot of the chart in your post.
In an analysis of clinical trials in the United States (2015-2019), the FDA found that of 102,596 participants, 78% were white, 16% were Black, and 2% were Asian. Given the incidence rates for this type of cancer, would a similar demographic breakdown be appropriate for the clinical trial shared by your classmate? Explain why or why not.
What recruitment goals should researchers set for participants in this clinical trial? What strategies might researchers use to meet these goals?
Eligibility criteria are necessary for clinical trials to define the patient population under study, isolate the potential effect of an investigational drug, and ensure that the trial is conducted safely. However, excessive or overly rigid eligibility criteria may impair the rate of trial accrual, restrict patient access to investigational drugs, and limit the ability to generalize the results to the broader population of patients who will ultimately have access to the treatment.
Look at the exclusion criteria for the clinical trial shared by your classmate. Are any of the following groups excluded?
Children (<13 years old) The elderly (>65 years old)
Pregnant women
Lactating women
People with chronic diseases (heart disease, hypertension, diabetes, etc.)
What implications do these exclusions have for the generalizability of the results of this clinical trial?
List two questions that someone might have about participating in this clinical trial.
Grading

To see how this assignment will be graded, click on the three dots in the upper right corner of this page, then click “Show Rubric”. If you’re reviewing this assignment using the Canvas mobile app, the rubric is in

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