Cardiovascular and Respiratory Systems

As an advanced practice nurse, it is your
responsibility to recommend appropriate treatment options for patients with
cardiovascular disorders. To ensure the safety and effectiveness of drug
therapy, advanced practice nurses must consider aspects that might influence
pharmacokinetic and pharmacodynamic processes such as medical history, other
drugs currently prescribed, and individual patient factors.

To Prepare
Review the Resources for this module and consider the
impact of potential pharmacotherapeutics for cardiovascular disorders
introduced in the media piece.
Review the case study assigned by your Instructor for
this Assignment.
Select one the following factors: genetics, gender,
ethnicity, age, or behavior factors.
Reflect on how the factor you selected might influence
the patients pharmacokinetic and pharmacodynamic processes.
Consider how changes in the pharmacokinetic and
pharmacodynamic processes might impact the patients recommended drug
therapy.
Think about how you might improve the patients drug
therapy plan based on the pharmacokinetic and pharmacodynamic changes.
Reflect on whether you would modify the current drug treatment or provide
an alternative treatment option for the patient.

Case Study
Patient HM has a history
of atrial fibrillation and a transient ischemic attack (TIA). The patient has
been diagnosed with type 2 diabetes, hypertension, hyperlipidemia,
and ischemic heart disease. Drugs currently prescribed include the
following:
Warfarin 5 mg daily
MWF and 2.5 mg daily T, TH, Sat, Sun
Aspirin 81 mg daily
Metformin 1000 mg po
bid
Glyburide 10 mg bid
Atenolol 100 mg po
daily
Motrin 200 mg 13
tablets every 6 hours as needed for pain

Write a 2- to 3-page paper that addresses the following:
Explain how the factor you selected might influence the
pharmacokinetic and pharmacodynamic processes in the patient from the case
study you were assigned.
Describe how changes in the processes might impact the
patients recommended drug therapy. Be specific and provide examples.
Explain how you might improve the patients drug
therapy plan and explain why you would make these recommended
improvements.
Reminder:
-The reference page should include all references cited in the
assignment in correct APA format.
-Some course
assignments may require the use of more than 2 credible outside resources.
In these cases, the minimum number of outside sources
specified in the instructions for the assignment will be applied in the
grading of these course assignments
Credible sources include scholarly peer-reviewed journal articles,
evidence-based resources, and professional (.org), educational (.edu), and
government websites (.gov). Commercial websites (.com) are not considered
credible sources. Please note: When selecting articles for course assignments,
you are advised (unless you are referencing seminal information) to focus on
work published within the past five years.

Required Readings

Rosenthal, L. D., & Burchum, J. R. (2021).
Lehnes pharmacotherapeutics for advanced practice nurses and physician
assistants (2nd ed.) St. Louis, MO: Elsevier.
Chapter
33, Review of Hemodynamics (pp. 285289)
Chapter
37, Diuretics (pp. 290296)
Chapter
38, Drugs Acting on the Renin-Angiotensin-Aldosterone System (pp.
297307)
Chapter
39, Calcium Channel Blockers (pp. 308312)
Chapter
40, Vasodilators (pp. 313317)
Chapter
41, Drugs for Hypertension (pp. 316324)
Chapter
42, Drugs for Heart Failure (pp. 325336)
Chapter
43, Antidysrhythmic Drugs (pp. 337348)
Chapter
44, Prophylaxis of Atherosclerotic Cardiovascular Disease: Drugs That
Help Normalize Cholesterol and Triglyceride Levels (pp. 349363)
Chapter
45, Drugs for Angina Pectoris (pp. 364371)
Chapter
46, Anticoagulant and Antiplatelet Drugs (pp. 372388)

Last Completed Projects