Describe the physiology of blood pressure control. Causes of Primary Hypertension may include overactivity of the SNS; overactivity of the RAAS; alterations in other neurohumoral mediators of blood volume and vasomotor tone such as ANP, BNP, and adrenomedullin; inflammation; a complex interaction involving insulin resistance and endothelial function; and obesity-related hormonal changes.

Initial Post: Describe the physiology of blood pressure control. Causes of Primary Hypertension may include overactivity of the SNS; overactivity of the RAAS; alterations in other neurohumoral mediators of blood volume and vasomotor tone such as ANP, BNP, and adrenomedullin; inflammation; a complex interaction involving insulin resistance and endothelial function; and obesity-related hormonal changes. Select 3 of the above potential causes and explain the pathophysiologic mechanisms of primary hypertension.
Response #1 Post a response to one peer in your discussion group. In the post identify the organ damage that can occur as a result of Hypertension. Describe the pathophysiologic process of the organ damage.
Response #2 Orthostatic hypotension can occur as an adverse effect of medications used to manage hypertension. Go back to your initial post and describe the pathophysiologic process that causes orthostatic hypotension.

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