)Discuss all the different ways and mechanisms that eukaryotes use to regulate gene expression.

1)How many of these strains of E. coli would have no ß-galactosidase activity?
2)If a mutation caused these things to occur, how would it affect the expression of the lac operon? (Consider each occurrence separately, not all together.)
1. adenylate cyclase stops working
2. CAP can no longer bind to DNA
3. CAP can no longer bind to cAMP

3)Discuss all the different ways and mechanisms that eukaryotes use to regulate gene expression.
4)Discuss the similarities and differences when it comes to how prokaryotes and eukaryotes regulate their genes. Be sure to frame your answer around the content as it is presented in this course.
5)The alpha- and beta-hemoglobin genes are expressed at different times during the human life cycle (i.e. embryo, fetus, adult).
1. How might this explain the role that each of these plays in human development?
2. How could this hypothesis be tested?

6)Why might the locations of introns and exons be the same in both alpha- and beta-hemoglobin genes?
7)E. coli brings lactose into its cell by using an enzyme called Lac Permease. Once the lactose is inside, another enzyme called ß-galactosidase converts the lactose into galactose and glucose.
1. How is E. coli’s way of dealing with lactose similar to how your cells do it?
2. How is it different?

8)Why do lactose intolerant people have problems when they consume dairy products? Be sure to frame your answer within the context of the genetics and biochemistry involved.
9)Match each formatting of “white” to what it represents in genetics.

white

WHITE (all capital letters)

white (in italics)
1.
phenotype
2.
gene
3.
protein

10)If a fruit fly experienced a mutation that made it homozygous in both the brown and sepia genes, what would be its eye color?
Question 10 options:
pink
white
red
no eyes

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