Explain why nitroglycerine is usually not given orally and give an example of another drug that is effected by the route of administration.

Explain why nitroglycerine is usually not given orally and give an example of another drug that is effected by the route of administration.
Why different routes of administration are utilized.
What effect do the different routes of administration have on the bioavailability of the drug?
Be sure to address all three items

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