. In your opinion, when did the U.S. Public Health Service Syphilis Study at Tuskegee become unethical? Was it in the 1940s when penicillin became the recommended drug for treatment of syphilis and researchers did not offer it to the subjects?

Please provide the answers to the questions in the following format: Question 1 Answer 1 Question 2 Answer 2 etc. Also, please cite in AMA format. Thank you 🙂 1. In your opinion, when did the U.S. Public Health Service Syphilis Study at Tuskegee become unethical? Was it in the 1940s when penicillin became the recommended drug for treatment of syphilis and researchers did not offer it to the subjects? or were there other issues with the study that raised ethical questions? 2. Did race play a factor in determining whether the Tuskegee /Guatemala studies were ethically conducted? Why or why not? 3a. How might racially biased assumptions affect clinical drug trials (i.e. studies affecting the treatment and prevention of disease)? 3b. Should the ethical guidance for protections of human subjects ever explicitly incorporate notions of race or ethnicity? Why or why not? 4. How are other vulnerable populations protected from circumstances of this nature occurring in the future? These are the resources to use: 1. https://www.youtube.com/watch?v=3KL7lcWMkz0 2. https://www.cdc.gov/tuskegee/timeline.htm 3. https://www.theguardian.com/us-news/2015/apr/02/johns-hopkins-lawsuit-deliberate-std-infections-guatemala 4. https://bioethicsarchive.georgetown.edu/pcsbi/sites/default/files/Ethically%20Impossible%20(with%20linked%20historical%20documents)%202.7.13.pdf 5. https://www.medscape.com/viewarticle/741668