Should chronic kidney disease be considered a potential threat issue for mortality as well as ESRD in patients with no hypertension as observed in hypertensive individuals?

Discussion Question
This is what we are writing about: Should chronic kidney disease be considered a potential threat issue for mortality as well as ESRD in patients with no hypertension as observed in hypertensive individuals? We need a problem statement and research question.
Begin your discussion by sharing your problem statement and research question. Next, discuss your sampling plan. In addition, discuss your research design. Consider the following as you craft your response.
Sampling
How will the sample be selected?
What type of sampling method is used? Is it appropriate to the design?
Does the sample reflect the population as identified in the problem or purpose statement?
Is the sample size appropriate? Why or why not?
To what population may the findings be generalized? What are the limitations in generalizability?
Research design
What type of design will be used?
Does the design seem to flow from the proposed research problem, theoretical framework, literature review, and hypothesis?

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