Write a research essay on a drug including a synthesis and mechanism description (Drug is: Vigabatrin).
· Brief background and introduction of the drug. This may include items such as historical importance, discovery and/or extraction development, disease treatment, biological activity, mechanism of action, and/or pharmaceutical treatment.
· Thorough descriptions of the syntheses and reactions. A well-designed, properly formatted figure containing each synthesis should be included and drawn using a chemical drawing program such as ChemDraw. A thorough description and explanation of the significance of the synthesis and reactions should accompany the figure.
· Complete mechanisms for the key reactions in the syntheses. Draw reaction mechanisms including appropriate mechanism arrows and intermediates should be included for the key steps in the synthesis.
· Key experimental reaction considerations. Describe any experiment reaction conditions that were unique or significant to each particular synthesis.
· Explain and discuss the main differences in the synthetic routes that were chosen.
For an example of a synthetic review paper, see: Zhang, X.; Xiao, Z.; Xu, H. Beilstein J. Org. Chem. 2019, 15, 1984–1995. doi:10.3762/bjoc.15.194
RUBRIC:
Drug:
Given synthesis as guide:
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